Enzyme Capacity Constraints

An enzyme capacity constraint states that a reaction rate is proportional to the concentration of the catalysing enzyme. The proportionality constant (capacity parameter) can be a constant or a function of model parameters such as the growth rate.

ID Enzyme Reaction Direction Type Formula
R_transport_enzyme_forward_capacity R_transport_enzyme R_transport forward <= {k_transporter_efficiency_foreward: {FunctionID: 'k_transporter_efficiency_foreward'
FunctionType: 'michaelisMenten'
IndependentVariable: 'M_substrate_e'
FunctionParameters: {Vmax: '1.0'
Km: '1.0'}}}
R_metabolism1_enzyme_forward_capacity R_metabolism1_enzyme R_metabolism1 forward <= {k_metabolism1_efficiency_foreward: {FunctionID: 'k_metabolism1_efficiency_foreward'
FunctionType: 'constant'
IndependentVariable: 'growth_rate'
FunctionParameters: {C: '0.3'}}}
R_metabolism2_enzyme_forward_capacity R_metabolism2_enzyme R_metabolism2 forward <= {k_metabolism2_efficiency_foreward: {FunctionID: 'k_metabolism2_efficiency_foreward'
FunctionType: 'constant'
IndependentVariable: 'growth_rate'
FunctionParameters: {C: '1.0'}}}
R_transport_enzyme_backward_capacity R_transport_enzyme R_transport backward <= {k_transporter_efficiency_backward: {FunctionID: 'k_transporter_efficiency_backward'
FunctionType: 'michaelisMenten'
IndependentVariable: 'M_substrate_e'
FunctionParameters: {Vmax: '1.0'
Km: '1.0'}}}
R_metabolism1_enzyme_backward_capacity R_metabolism1_enzyme R_metabolism1 backward <= {k_metabolism1_efficiency_backward: {FunctionID: 'k_metabolism1_efficiency_backward'
FunctionType: 'constant'
IndependentVariable: 'growth_rate'
FunctionParameters: {C: '1.0'}}}
R_metabolism2_enzyme_backward_capacity R_metabolism2_enzyme R_metabolism2 backward <= {k_metabolism2_efficiency_backward: {FunctionID: 'k_metabolism2_efficiency_backward'
FunctionType: 'constant'
IndependentVariable: 'growth_rate'
FunctionParameters: {C: '1.0'}}}