Machinery-capacity constraints

A machinery capacity constraint states that the rate of a macromolecular process is proportional to the concentration of the catalysing machine. The proportionality constant (capacity parameter) can be a constant or a function of model parameters such as the growth rate.

ID Process Type Formula
P_SEC_capacity P_SEC = {secretion_capacity: {FunctionID: 'secretion_capacity'
FunctionType: 'linear'
IndependentVariable: 'growth_rate'
FunctionParameters: {A: '425660.470793603'
C: '-24979.0894512654'
xMin: '0.26'
xMax: '1.9'
yMin: '-inf'
yMax: 'inf'}}}
P_TA_capacity P_TA =
{ribosome_efficiency_MM: {FunctionID: 'ribosome_efficiency_MM'
FunctionType: 'michaelisMenten'
IndependentVariable: 'growth_rate'
FunctionParameters: {Vmax: '97200.0'
Km: '0.5'
yMin: '32400.0'}}}, {fraction_active_ribosomes: {FunctionID: 'fraction_active_ribosomes'
FunctionType: 'exponential'
IndependentVariable: 'growth_rate'
FunctionParameters: {Lambda: '-0.083333'}}}
P_CHP_capacity P_CHP = {chaperone_efficiency_LM: {FunctionID: 'chaperone_efficiency_LM'
FunctionType: 'linear'
IndependentVariable: 'growth_rate'
FunctionParameters: {A: '25942.770707548'
C: '5711.3441235355'
xMin: '0.26'
xMax: '1.9'
yMin: '-inf'
yMax: 'inf'}}}
P_TSC_capacity P_TSC =
P_REP_capacity P_REP =
P_RNADEG_capacity P_RNADEG =